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Displaying 4 of 4 results SARS-CoV-2 clear search
This agent-based model explores the dynamics between human behavior and vaccination strategies during COVID-19 pandemics. It examines how individual risk perceptions influence behaviors and subsequently affect epidemic outcomes in a simulated metropolitan area resembling New York City from December 2020 to May 2021.
Agents modify their daily activities—deciding whether to travel to densely populated urban centers or stay in less crowded neighborhoods—based on their risk perception. This perception is influenced by factors such as risk perception threshold, risk tolerance personality, mortality rate, disease prevalence, and the average number of contacts per agent in crowded settings. Agent characteristics are carefully calibrated to reflect New York City demographics, including age distribution and variations in infection probability and mortality rates across these groups. The agents can experience six distinct health statuses: susceptible, exposed, infectious, recovered from infection, dead, and vaccinated (SEIRDV). The simulation focuses on the Iota and Alpha variants, the dominant strains in New York City during the period.
We simulate six scenarios divided into three main categories:
1. A baseline model without vaccinations where agents exhibit no risk perception and are indifferent to virus transmission and disease prevalence.
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A curious aspect of the Covid-19 pandemic is the clustering of outbreaks. Evidence suggests that 80\% of people who contract the virus are infected by only 19% of infected individuals, and that the majority of infected individuals faile to infect another person. Thus, the dispersion of a contagion, $k$, may be of more use in understanding the spread of Covid-19 than the reproduction number, R0.
The Virus Transmission with Super-spreaders model, written in NetLogo, is an adaptation of the canonical Virus Transmission on a Network model and allows the exploration of various mitigation protocols such as testing and quarantines with both homogenous transmission and heterogenous transmission.
The model consists of a population of individuals arranged in a network, where both population and network degree are tunable. At the start of the simulation, a subset of the population is initially infected. As the model runs, infected individuals will infect neighboring susceptible individuals according to either homogenous or heterogenous transmission, where heterogenous transmission models super-spreaders. In this case, k is described as the percentage of super-spreaders in the population and the differing transmission rates for super-spreaders and non super-spreaders. Infected individuals either recover, at which point they become resistant to infection, or die. Testing regimes cause discovered infected individuals to quarantine for a period of time.
In this model, the spread of a virus disease in a network consisting of school pupils, employed, and umemployed people is simulated. The special feature in this model is the distinction between different types of links: family-, friends-, school-, or work-links. In this way, different governmental measures can be implemented in order to decelerate or stop the transmission.
CINCH1 (Covid-19 INfection Control in Hospitals), is a prototype model of physical distancing for infection control among staff in University College London Hospital during the Covid-19 pandemic, developed at the University of Leeds, School of Geography. It models the movement of collections of agents in simple spaces under conflicting motivations of reaching their destination, maintaining physical distance from each other, and walking together with a companion. The model incorporates aspects of the Capability, Opportunity and Motivation of Behaviour (COM-B) Behaviour Change Framework developed at University College London Centre for Behaviour Change, and is aimed at informing decisions about behavioural interventions in hospital and other workplace settings during this and possible future outbreaks of highly contagious diseases. CINCH1 was developed as part of the SAFER (SARS-CoV-2 Acquisition in Frontline Health Care Workers – Evaluation to Inform Response) project
(https://www.ucl.ac.uk/behaviour-change/research/safer-sars-cov-2-acquisition-frontline-health-care-workers-evaluation-inform-response), funded by the UK Medical Research Council. It is written in Python 3.8, and built upon Mesa version 0.8.7 (copyright 2020 Project Mesa Team).