Identifying how organisms respond to environmental stressors remains of central importance as human impacts continue to shift the environmental conditions for countless species. Some mammals are able to mitigate these environmental stressors at the cellular level, but the mechanisms by which cells are able to do this and how these strategies vary among species is not well understood. At the cellular level, it is difficult to identify the temporal dynamics of the system through empirical data because fine-grained time course samples are both incomplete and limited by available resources. To help identify the mechanisms by which animal cells mitigate extreme environmental conditions, we propose an agent-based model to capture the dynamics of the system. In the model, agents are regulatory elements and genes, and are able to impact the behaviors of each other. Rather than imposing rules for these interactions among agents, we will begin with randomized sets of rules and calibrate the model based on empirical data of cellular responses to stress. We will apply a common-garden framework to cultured cells from 16 mammalian species, which will yield genomic data and measures of cell morphology and physiology when exposed to different levels of temperature, glucose, and oxygen. These species include humans, dolphins, bats, and camels, among others, which vary in how they respond to environmental stressors, offering a comparative approach for identifying mechanistic rules whereby cells achieve robustness to environmental stressors. For calibration of the model, we will iteratively select for rules that best lead to the emergent outcomes observed in the cellular assays. Our model is generalized for any species, any cell type, and any environmental stressor, offering many applications of the model beyond our study. This study will increase our understanding of how organisms mitigate environmental stressors at the cellular level such that we can better address how organisms are impacted by and respond to extreme environmental conditions.

Local scale mobility, namely foraging, leads to global population dispersal. Agents acquire information about their environment in two ways, one individual and one social. See also http://www.openabm.org/model/3846/

Models land-use, perception, and biocultural interactions between two forager populations.

This is a relatively simple foraging-radius model, as described first by Robert Kelly, that allows one to quantify the effect of increased logistical mobility (as represented by increased effective foraging radius, r_e) on the likelihood that 2 randomly placed central place foragers will encounter one another within 5000 time steps.

This is an agent-based model that allows to test alternative designs for three model components. The model was built using the LUDAS design strategy, while each alternative is in line with the strategy. Using the model, it can be shown that alternative designs, though built on the same strategy, lead to different land-use patterns over time.

The TechNet_04 is an abstract model that embeds a simple cultural tranmission process in an environment where interaction is structured by spatially-situated networks.

Agent-Based-Modeling - space colonization
ask me for the .nlogo model
WHAT IS IT?
The goal of this project is to simulate with NetLogo (v6.2) a space colonization of humans, starting from Earth, into the Milky Way.

HOW IT WORKS
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This NetLogo model implements the Walk Away strategy in a spatial public goods game, where individuals have the ability to leave groups with insufficient levels of cooperation.

B3GET simulates populations of virtual organisms evolving over generations, whose evolutionary outcomes reflect the selection pressures of their environment. The model simulates several factors considered important in biology, including life history trade-offs, investment in fighting ability and aggression, sperm competition, infanticide, and competition over access to food and mates. Downloaded materials include starting genotype and population files. Edit the these files and see what changes occur in the behavior of virtual populations!

View the B3GET user manual here.

The current rate of production and consumption of meat poses a problem both to peoples’ health and to the environment. This work aims to develop a simulation of peoples’ meat consumption behaviour in Britain using agent-based modelling. The agents represent individual consumers. The key variables that characterise agents include sex, age, monthly income, perception of the living cost, and concerns about the impact of meat on the environment, health, and animal welfare. A process of peer influence is modelled with respect to the agents’ concerns. Influence spreads across two eating networks (i.e. co-workers and household members) depending on the time of day, day of the week, and agents’ employment status. Data from a representative sample of British consumers is used to empirically ground the model. Different experiments are run simulating interventions of application of social marketing campaigns and a rise in price of meat. The main outcome is the average weekly consumption of meat per consumer. A secondary outcome is the likelihood of eating meat.