EMMIT is an end-user developed agent-based simulation of malaria transmission. The simulation’s development is a case study demonstrating an approach for non-technical investigators to easily develop useful simulations of complex public health problems. We focused on malaria transmission, a major global public health problem, and insecticide resistance (IR), a major problem affecting malaria control. Insecticides are used to reduce transmission of malaria caused by the Plasmodium parasite that is spread by the Anopheles mosquito. However, the emergence and spread of IR in a mosquito population can diminish the insecticide’s effectiveness. IR results from mutations that produce behavioral changes or biochemical changes (such as detoxification enhancement, target site alterations) in the mosquito population that provide resistance to the insecticide. Evolutionary selection for the IR traits reduces the effectiveness of an insecticide favoring the resistant mosquito population. It has been suggested that biopesticides, and specifically those that are Late Life Acting (LLA), could address this problem. LLA insecticides exploit Plasmodium’s approximate 10-day extrinsic incubation period in the mosquito vector, a delay that limits malaria transmission to older infected mosquitoes. Since the proposed LLA insecticide delays mosquito death until after the exposed mosquito has a chance to produce several broods of offspring, reducing the selective pressure for resistance, it delays IR development and gives the insecticide longer effectivity. Such insecticides are designed to slow the evolution of IR thus maintaining their effectiveness for malaria control. For the IR problem, EMMIT shows that an LLA insecticide could work as intended, but its operational characteristics are critical, primarily the mean-time-to-death after exposure and the associated standard deviation. We also demonstrate the simulation’s extensibility to other malaria control measures, including larval source control and policies to mitigate the spread of IR. The simulation was developed using NetLogo as a case study of a simple but useful approach to public health research.

A friendship game is a kind of network game: a game theory model on a network. This is a NetLogo model of an agent-based adaptation of “‘Friendship-based’ Games” by PJ Lamberson. The agents reach an equilibrium that depends on the strategy played and the topology of the network.

This is a model of innovation implementation inside an organization. It characterizes an innovation as a set of distributed and technically interdependent tasks performed by a number of different and socially interconnected frontline workers.

The Palaeo-Agulhas Plain formed an important habitat exploited by Pleistocene hunter-gatherer populations during periods of lower sea level. This productive, grassy habitat would have supported numerous large-bodied ungulates accessible to a population of skilled hunters with the right hunting technology. It also provided a potentially rich location for plant food collection, and along its shores a coastline that moved with the rise and fall of sea levels. The rich archaeological and paleontological records of Pleistocene sites along the modern Cape south coast of South Africa, which would have overlooked the Palaeo-Agulhas Plain during Pleistocene times of lower sea level, provides a paleoarchive of this extinct ecosystem. In this paper, we present a first order illustration of the “palaeoscape modeling” approach advocated by Marean et al. (2015). We use a resourcescape model created from modern studies of habitat productivity without the Palaeo-Agulhas Plain. This is equivalent to predominant Holocene conditions. We then run an agent-based model of the human foraging system to investigate several research questions. Our agent-based approach uses the theoretical framework of optimal foraging theory to model human foraging decisions designed to optimize the net caloric gains within a complex landscape of spatially and temporally variable resources. We find that during the high sea-levels of MIS 5e (+5-6 m asl) and the Holocene, the absence of the Plain left a relatively poor food base supporting a much smaller population relying heavily on edible plant resources from the current Cape flora. Despite high species diversity of plants with edible storage organs, and marine invertebrates, encounter rates with highly profitable resources were low. We demonstrate that without the Palaeo-Agulhas Plain, human populations must have been small and low density, and exploited plant, mammal, and marine resources with relatively low caloric returns. The exposure and contraction of the Palaeo-Agulhas Plain was likely the single biggest driver of behavioral change during periods of climate change through the Pleistocene and into the transition to the Holocene.

The agent-based perspective allows insights on how behaviour of firms, guided by simple economic rules on the micro-level, is dynamically influenced by a complex environment in regard to the assumed relocation, decision-making hypotheses. Testing various variables sensitive to initial conditions, increased environmental regulations targeting global trade and upward shifting wage levels in formerly offshore production locations have shown to be driving and inhibiting mechanisms of this socio-technical system. The dynamic demonstrates a shift from predominantly cited economic reasoning for relocation strategies towards sustainability aspects, pressingly changing these realities on an environmental and social dimension. The popular debate is driven by increased environmental awareness and the proclaimed fear of robots killing jobs. In view of reshoring shaping the political agenda, interest in the phenomenon has recently been fuelled by the rise of populism and protectionism.

A computational model of a classic small group study by Alex Bavelas. This computational model was designed to explore the difficulty in translating a seemingly simple real-world experiment into a computational model.

Decision-makers often have to act before critical times to avoid the collapse of ecosystems using knowledge \textcolor{red}{that can be incomplete or biased}. Adaptive management may help managers tackle such issues. However, because the knowledge infrastructure required for adaptive management may be mobilized in several ways, we study the quality and the quantity of knowledge provided by this knowledge infrastructure. In order to analyze the influence of mobilized knowledge, we study how the following typology of knowledge and its use may impact the safe operating space of exploited ecosystems: 1) knowledge of the past based on a time series distorted by measurement errors; 2) knowledge of the current systems’ dynamics based on the representativeness of the decision-makers’ mental models of the exploited ecosystem; 3) knowledge of future events based on decision-makers’ likelihood estimates of extreme events based on modeling infrastructure (models and experts to interpret them) they have at their disposal. We consider different adaptive management strategies of a general regulated exploited ecosystem model and we characterize the robustness of these strategies to biased knowledge. Our results show that even with significant mobilized knowledge and optimal strategies, imperfect knowledge may still shrink the safe operating space of the system leading to the collapse of the system. However, and perhaps more interestingly, we also show that in some cases imperfect knowledge may unexpectedly increase the safe operating space by suggesting cautious strategies.
The code enables to calculate the safe operating spaces of different managers in the case of biased and unbiased knowledge.

The development and popularisation of new energy vehicles have become a global consensus. The shortage and unreasonable layout of electric vehicle charging infrastructure (EVCI) have severely restricted the development of electric vehicles. In the literature, many methods can be used to optimise the layout of charging stations (CSs) for producing good layout designs. However, more realistic evaluation and validation should be used to assess and validate these layout options. This study suggested an agent-based simulation (ABS) model to evaluate the layout designs of EVCI and simulate the driving and charging behaviours of electric taxis (ETs). In the case study of Shenzhen, China, GPS trajectory data were used to extract the temporal and spatial patterns of ETs, which were then used to calibrate and validate the actions of ETs in the simulation. The ABS model was developed in a GIS context of an urban road network with travelling speeds of 24 h to account for the effects of traffic conditions. After the high-resolution simulation, evaluation results of the performance of EVCI and the behaviours of ETs can be provided in detail and in summary. Sensitivity analysis demonstrates the accuracy of simulation implementation and aids in understanding the effect of model parameters on system performance. Maximising the time satisfaction of ET users and reducing the workload variance of EVCI were the two goals of a multiobjective layout optimisation technique based on the Pareto frontier. The location plans for the new CS based on Pareto analysis can significantly enhance both metrics through simulation evaluation.

In 1985 Dr Michael Palmiter, a high school teacher, first built a very innovative agent-based model called “Simulated Evolution” which he used for teaching the dynamics of evolution. In his model, students can see the visual effects of evolution as it proceeds right in front of their eyes. Using his schema, small linear changes in the agent’s genotype have an exponential effect on the agent’s phenotype. Natural selection therefore happens quickly and effectively. I have used his approach to managing the evolution of competing agents in a variety of models that I have used to study the fundamental dynamics of sustainable economic systems. For example, here is a brief list of some of my models that use “Palmiter Genes”:
- ModEco - Palmiter genes are used to encode negotiation strategies for setting prices;
- PSoup - Palmiter genes are used to control both motion and metabolic evolution;
- TpLab - Palmiter genes are used to study the evolution of belief systems;
- EffLab - Palmiter genes are used to study Jevon’s Paradox, EROI and other things.

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How do households alter their spending patterns when they experience changes in income? This model answers this question using a random assignment scheme where spending patterns are copied from a household in the new income bracket.